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Phenotypic screens identify SCAF1 as critical activator of RNAPII elongation and global transcription. Bhandare P, Narain A, Hofstetter J, Rummel T, Wenzel J, Schülein-Völk C, Lamer S, Eilers U, Schlosser A, Eilers M, Erhard F, Wolf E. Nucleic Acids Res. 2024 Dec 19:gkae1219. doi: 10.1093/nar/gkae1219. Online ahead of print.
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Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts. Trifault B, Mamontova V, Cossa G, Ganskih S, Wei Y, Hofstetter J, Bhandare P, Baluapuri A, Nieto B, Solvie D, Ade CP, Gallant P, Wolf E, Larsen DH, Munschauer M, Burger K. Nucleic Acids Res. 2024 Apr 12;52(6):3050-3068. doi: 10.1093/nar/gkae022.
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Mapping of a major QTL for increased robustness and detection of genome assembly errors in Asian seabass (Lates calcarifer). Shen X, Niu YC, Uichanco JAV, Phua N, Bhandare P, Thevasagayam NM, Prakki SRS, Orbán L. BMC Genomics. 2023 Aug 10;24(1):449. doi: 10.1186/s12864-023-09513-z.
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The glycolytic enzyme ALDOA and the exon junction complex protein RBM8A are regulators of ribosomal biogenesis. Schwarz JD, Lukassen S, Bhandare P, Eing L, Snaebjörnsson MT, García YC, Kisker JP, Schulze A, Wolf E. Front Cell Dev Biol. 2022 Sep 14;10:954358. doi: 10.3389/fcell.2022.954358. eCollection 2022.
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Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma. Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JD. Cancer Immunol Res. 2022 Apr 1;10(4):482-497. doi: 10.1158/2326-6066.CIR-21-0778.
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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination. Narain A, Bhandare P, Adhikari B, Backes S, Eilers M, Dölken L, Schlosser A, Erhard F, Baluapuri A, Wolf E. Mol Cell. 2021 Aug 5;81(15):3110-3127.e14. doi: 10.1016/j.molcel.2021.06.016. Epub 2021 Jul 6.
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PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S, Wolf E. Nat Chem Biol. 2020 Nov;16(11):1179-1188. doi: 10.1038/s41589-020-00652-y. Epub 2020 Sep 28.
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MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang SY, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E. Mol Cell. 2019 May 16;74(4):674-687.e11. doi: 10.1016/j.molcel.2019.02.031. Epub 2019 Mar 27.
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BAC-pool sequencing and analysis confirms growth-associated QTLs in the Asian seabass genome. Shen X, Ngoh SY, Thevasagayam NM, Prakki SR, Bhandare P, Tan AW, Tan GQ, Singh S, Phua NC, Vij S, Orbán L. Sci Rep. 2016 Nov 8;6:36647. doi: 10.1038/srep36647.
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| | Last update Publications 20.01.2025 |
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