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Doctoral Researcher


Name Zhiyi Chen
Affiliation
Rudolf Virchow Center for Integrative and Translational Bioimaging
Street Josef-Schneider-Str. 2 D15
Zip Code 97080
City Würzburg
Email E-mail
Telephone +49 931 31- 86341
Homepage Homepage
Section Biomedicine
Title of Thesis Project Targeting selenocysteine metabolism in chemoterapy refractory tumors (TarSel)
Primary Supervisor Prof. José Pedro Friedmann Angeli, PhD
Member of Thesis Committee Prof. Dr. Svenja Meierjohann
Prof. Dr. Elmar Wolf now University Kiel
Conference Contribution
Publication

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis. Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, Schaefer EL, Ekpo I, Schmitz W, Horling A, Imming P, Miyamoto S, Wehman AM, Genaro-Mattos TC, Mirnics K, Kumar L, Klein-Seetharaman J, Meierjohann S, Weigand I, Kroiss M, Bornkamm GW, Gomes F, Netto LES, Sathian MB, Konrad DB, Covey DF, Michalke B, Bommert K, Bargou RC, Garcia-Saez A, Pratt DA, Fedorova M, Trumpp A, Conrad M, Friedmann Angeli JP. Nature. 2024 Feb;626(7998):401-410. doi: 10.1038/s41586-023-06878-9. Epub 2024 Jan 31.

LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma. Alborzinia H, Chen Z, Yildiz U, Freitas FP, Vogel FCE, Varga JP, Batani J, Bartenhagen C, Schmitz W, Büchel G, Michalke B, Zheng J, Meierjohann S, Girardi E, Espinet E, Flórez AF, Dos Santos AF, Aroua N, Cheytan T, Haenlin J, Schlicker L, Xavier da Silva TN, Przybylla A, Zeisberger P, Superti-Furga G, Eilers M, Conrad M, Fabiano M, Schweizer U, Fischer M, Schulze A, Trumpp A, Friedmann Angeli JP. EMBO Mol Med. 2023 Aug 7;15(8):e18014. doi: 10.15252/emmm.202318014. Epub 2023 Jul 12.

Expression of a novel complement C3 gene in the razor clam Sinonovacula constricta and its role in innate immune response and hemolysis. Peng M, Niu D, Chen Z, Lan T, Dong Z, Tran TN, Li J. Dev Comp Immunol. 2017 Aug;73:184-192. doi: 10.1016/j.dci.2017.03.027. Epub 2017 Apr 1.

Complement C3 gene: Expression characterization and innate immune response in razor clam Sinonovacula constricta. Peng M, Niu D, Wang F, Chen Z, Li J. Fish Shellfish Immunol. 2016 Aug;55:223-32. doi: 10.1016/j.fsi.2016.05.024. Epub 2016 May 24.

Last update Publications 03.02.2024

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