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Acute systemic knockdown of Atg7 is lethal and causes pancreatic destruction in shRNA transgenic mice. Mainz L, Sarhan MAFE, Roth S, Sauer U, Kalogirou C, Eckstein M, Gerhard-Hartmann E, Seibert HD, Voelker HU, Geppert C, Rosenwald A, Eilers M, Schulze A, Diefenbacher M, Rosenfeldt MT. Autophagy. 2022 Dec;18(12):2880-2893. doi: 10.1080/15548627.2022.2052588. Epub 2022 Mar 28.
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Autophagy Blockage Reduces the Incidence of Pancreatic Ductal Adenocarcinoma in the Context of Mutant Trp53. Mainz L, Sarhan MAFE, Roth S, Sauer U, Maurus K, Hartmann EM, Seibert HD, Rosenwald A, Diefenbacher ME, Rosenfeldt MT. Front Cell Dev Biol. 2022 Mar 16;10:785252. doi: 10.3389/fcell.2022.785252. eCollection 2022.
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| Last update Publications 21.01.2025 |
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