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Doctoral Researcher


Name Jakob Jung
Affiliation
IMIB Institute for Molecular Infection Biology
Street Josef-Schneider-Str. 2 D15
Zip Code 97080
City Würzburg
Email
Telephone
Homepage Homepage
Section Integrative Biology
Title of Thesis Project Programming antisense oligonucleotides
Primary Supervisor Prof. Dr. Jörg Vogel
Member of Thesis Committee Prof. Lars Barquist now University Toronto Canada
Ana Rita Gontao Brochado PhD now University of Tübingen
Prof. Dr. Thomas Dandekar
Conference Contribution
Publication

A comparative analysis of peptide-delivered antisense antibiotics using diverse nucleotide mimics. Ghosh C, Popella L, Dhamodharan V, Jung J, Dietzsch J, Barquist L, Höbartner C, Vogel J. RNA. 2024 May 16;30(6):624-643. doi: 10.1261/rna.079969.124.

Design and off-target prediction for antisense oligomers targeting bacterial mRNAs with the MASON web server. Jung J, Popella L, Do PT, Pfau P, Vogel J, Barquist L. RNA. 2023 May;29(5):570-583. doi: 10.1261/rna.079263.122. Epub 2023 Feb 7. 

INRI-seq enables global cell-free analysis of translation initiation and off-target effects of antisense inhibitors. Hör J, Jung J, Ðurica-Mitić S, Barquist L, Vogel J. Nucleic Acids Res. 2022 Dec 9;50(22):e128. doi: 10.1093/nar/gkac838. 

Comprehensive analysis of PNA-based antisense antibiotics targeting various essential genes in uropathogenic Escherichia coli. Popella L, Jung J, Do PT, Hayward RJ, Barquist L, Vogel J. Nucleic Acids Res. 2022 Jun 24;50(11):6435-6452. doi: 10.1093/nar/gkac362.

Global RNA profiles show target selectivity and physiological effects of peptide-delivered antisense antibiotics. Popella L, Jung J, Popova K, Ðurica-Mitić S, Barquist L, Vogel J. Nucleic Acids Res. 2021 May 7;49(8):4705-4724. doi: 10.1093/nar/gkab242.

Last update Publications 02.03.2024

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