Doctoral Researcher


Name Dörthe Gertzmann
Affiliation Chair of Biochemistry and Cell Biology
Chair of Biochemistry and Molecular Biology II
Street Am Hubland
Zip Code 97074
City Würzburg
Email E-mail
Telephone +49 931 31- 87435
Homepage Homepage
Section Biomedicine
Title of Thesis Project Regulation of cell cycle gene expression by YAP and MMB protein complexes
Primary Supervisor Prof. Dr. Stefan Gaubatz
Member of Thesis Committee Prof. Dr. Svenja Meierjohann
Prof. Dr. Christian Häring
Dr. Björn von Eyß, FLI Jena
Conference Contribution
Publication Personal Formatting

Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers. Jessen M, Gertzmann D, Liss F, Zenk F, Bähner L, Schöffler V, Schulte C, Maric HM, Ade CP, von Eyss B, Gaubatz S. Oncogene. 2024 Feb;43(8):578-593. doi: 10.1038/s41388-023-02926-w. Epub 2024 Jan 5.

Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration. Fetiva MC, Liss F, Gertzmann D, Thomas J, Gantert B, Vogl M, Sira N, Weinstock G, Kneitz S, Ade CP, Gaubatz S. Nucleic Acids Res. 2023 May 22;51(9):4266-4283. doi: 10.1093/nar/gkad107. 

Expression of the cytokinesis regulator PRC1 results in p53-pathway activation in A549 cells but does not directly regulate gene expression in the nucleus. Hanselmann S, Gertzmann D, Shin WJ, Ade CP, Gaubatz S. Cell Cycle. 2023 Feb;22(4):419-432. doi: 10.1080/15384101.2022.2122258. Epub 2022 Sep 22.
Last update Publications 13.01.2024