Doctoral Researcher


Name Frank Englert HIRI
Affiliation
Helmholtz Institute for RNA-based Infection Research HIRI
Street Josef-Schneider-Str. 2 D15
Zip Code 97080
City Würzburg
Email
Telephone +49 931 31- 86744
Homepage Homepage
Section Infection & Immunity
Title of Thesis Project Characterizing novel defense systems in bacteria
Primary Supervisor Prof. Chase L. Beisel now BIIE Basel Switzerland
Member of Thesis Committee Prof. Dr. rer. nat. Alexander Westermann
Ana Rita Gontao Brochado PhD now University of Tübingen
Prof. Dr. Franziska Faber
Conference Contribution
Publication

Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans. Benz F, Camara-Wilpert S, Russel J, Wandera KG, Čepaitė R, Ares-Arroyo M, Gomes-Filho JV, Englert F, Kuehn JA, Gloor S, Mestre MR, Cuénod A, Aguilà-Sans M, Maccario L, Egli A, Randau L, Pausch P, Rocha EPC, Beisel CL, Madsen JS, Bikard D, Hall AR, Sørensen SJ, Pinilla-Redondo R. Cell Host Microbe. 2024 Jun 12;32(6):875-886.e9. doi: 10.1016/j.chom.2024.04.016. Epub 2024 May 15. 

Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation. Wimmer F, Englert F, Wandera KG, Alkhnbashi OS, Collins SP, Backofen R, Beisel CL. Nucleic Acids Res. 2024 Jan 25;52(2):769-783. doi: 10.1093/nar/gkad1097.

Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons. Wimmer F, Mougiakos I, Englert F, Beisel CL. Mol Cell. 2022 Mar 17;82(6):1210-1224.e6. doi: 10.1016/j.molcel.2022.01.026. Epub 2022 Feb 24.

A TXTL-Based Assay to Rapidly Identify PAMs for CRISPR-Cas Systems with Multi-Protein Effector Complexes. Wimmer F, Englert F, Beisel CL. Methods Mol Biol. 2022;2433:391-411. doi: 10.1007/978-1-0716-1998-8_24.

A Hyperactive Form of the Zinc Cluster Transcription Factor Stb5 Causes YOR1 Overexpression and Beauvericin Resistance in Candida albicans. Ramírez-Zavala B, Manz H, Englert F, Rogers PD, Morschhäuser J. Antimicrob Agents Chemother. 2018 Nov 26;62(12):e01655-18. doi: 10.1128/AAC.01655-18. Print 2018

Last update Publications 18.05.2024