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Doctoral Researcher


Name Maximilian Englert
Affiliation Institute of Experimental Biomedicine
Chair of Experimental Biomedicine I
Street Josef-Schneider-Str. 2 D16
Zip Code 97080
City Würzburg
Email
Telephone
Homepage Homepage
Section Biomedicine
Title of Thesis Project Membrane receptor signaling in megakaryopoiesis and platelet biogenesis: studies in genetically modified mice
Primary Supervisor Zoltan Nagy PhD (Irland)
Member of Thesis Committee Prof. Dr. Katrin Heinze
Prof. Dr. Thomas Dandekar
Prof. Dr. Bernhard Nieswandt
Conference Contribution
Publication

Mutations of the dimerization site of glycoprotein (GP) VI result in abolished expression. Navarro S, Vögtle T, Groß N, Preu J, Englert M, Nieswandt B, Bösl MR, Stegner D. Thromb Res. 2023 Dec;232:89-92. doi: 10.1016/j.thromres.2023.10.016. Epub 2023 Oct 31.

Highly efficient platelet generation in lung vasculature reproduced by microfluidics. Zhao X, Alibhai D, Walsh TG, Tarassova N, Englert M, Birol SZ, Li Y, Williams CM, Neal CR, Burkard P, Cross SJ, Aitken EW, Waller AK, Beltrán JB, Gunning PW, Hardeman EC, Agbani EO, Nieswandt B, Hers I, Ghevaert C, Poole AW. Nat Commun. 2023 Jul 7;14(1):4026. doi: 10.1038/s41467-023-39598-9.

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo. Elgheznawy A, Öftering P, Englert M, Mott K, Kaiser F, Kusch C, Gbureck U, Bösl MR, Schulze H, Nieswandt B, Vögtle T, Hermanns HM. Front Immunol. 2023 Jun 8;14:1197894. doi: 10.3389/fimmu.2023.1197894. eCollection 2023.

Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice. Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, Dütting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z. Blood Adv. 2022 Sep 13;6(17):5184-5197. doi: 10.1182/bloodadvances.2021006545.

G6b-B regulates an essential step in megakaryocyte maturation. Becker IC, Nagy Z, Manukjan G, Haffner-Luntzer M, Englert M, Heib T, Vögtle T, Gross C, Bharti R, Dietrich S, Mott K, Heck J, Stegmaier S, Baranowsky A, Schinke T, Schlegel N, Heckel T, Stegner D, Pleines I, Ignatius A, Schulze H, Nieswandt B. Blood Adv. 2022 May 24;6(10):3155-3161. doi: 10.1182/bloodadvances.2021006151.

RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes. Heib T, Hermanns HM, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, Dütting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, Pleines I. Cell Rep. 2021 May 11;35(6):109102. doi: 10.1016/j.celrep.2021.109102.

Last update Publications 18.11.2023

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