Doctoral Researcher


Name Daniel Fleischauer
Affiliation Theodor-Boveri-Institute (Biocenter)
Chair of Biochemistry and Molecular Biology
Street Am Hubland
Zip Code 97074
City Würzburg
Email E-mail
Telephone +49 931 31- 83297
Homepage
Section Biomedicine
Title of Thesis Project Identification and Characterization of MYCN Complexes to target in Neuroblastoma Therapy
Primary Supervisor Prof. Dr. Martin Eilers
Member of Thesis Committee Jun.-Prof. Dr. Gabriele Büchel
Prof. Dr. Utz Fischer
Prof. Richard Bayliss, University of Leeds
Conference Contribution
Publication

The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex. Papadopoulos D, Ha SA, Fleischhauer D, Uhl L, Russell TJ, Mikicic I, Schneider K, Brem A, Valanju OR, Cossa G, Gallant P, Schuelein-Voelk C, Maric HM, Beli P, Büchel G, Vos SM, Eilers M. Mol Cell. 2024 Jun 6;84(11):2070-2086.e20. doi: 10.1016/j.molcel.2024.04.007. Epub 2024 May 3. 

MYC multimers shield stalled replication forks from RNA polymerase. Solvie D, Baluapuri A, Uhl L, Fleischhauer D, Endres T, Papadopoulos D, Aziba A, Gaballa A, Mikicic I, Isaakova E, Giansanti C, Jansen J, Jungblut M, Klein T, Schülein-Völk C, Maric H, Doose S, Sauer M, Beli P, Rosenwald A, Dobbelstein M, Wolf E, Eilers M. Nature. 2022 Dec;612(7938):148-155. doi: 10.1038/s41586-022-05469-4. Epub 2022 Nov 23. 
Last update Publications 11.05.2024