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Doctoral Researcher


Name Moutaz Helal
Affiliation Institute of Virology and Immunobiology

Mildred Scheel Early Career Center (MSNZ Würzburg)

Street Versbacher Str. 7
Zip Code 97078
City Würzburg
Email E-mail
Telephone +49 931 31- 84362
Additional Affiliation
Homepage Link to Homepage
Section Biomedicine
Title of Thesis Project Microenvironmental regulation of neoadjuvant chemotherapy resistance mechanisms in breast cancer and multiple myeloma
Primary Supervisor Angela Riedel-Lichorowicz PhD
Member of Thesis Committee Prof. Dr. Leo Rasche
Prof. Dr. Elmar Wolf now University Kiel
Prof. Dr. Georg Gasteiger
Publication

NFATc1 Fosters Allergic Contact Dermatitis Responses by Enhancing the Induction of IL-17-Producing CD8 Cells. Azeem M, Helal M, Klein-Hessling S, Serfling E, Goebeler M, Muhammad K, Kerstan A. J Invest Dermatol. 2025 Aug;145(8):1995-2006.e5. doi: 10.1016/j.jid.2024.11.014. Epub 2024 Dec 27.

Spatial transcriptomics reveals molecular cues underlying the site specificity of the adult mouse oral mucosa and its stem cell niches. Seubert AC, Krafft M, Bopp S, Helal M, Bhandare P, Wolf E, Alemany A, Riedel A, Kretzschmar K. Stem Cell Reports. 2024 Dec 10;19(12):1706-1719. doi: 10.1016/j.stemcr.2024.10.007. Epub 2024 Nov 27.

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma. John M, Helal M, Duell J, Mattavelli G, Stanojkovska E, Afrin N, Leipold AM, Steinhardt MJ, Zhou X, Žihala D, Anilkumar Sithara A, Mersi J, Waldschmidt JM, Riedhammer C, Kadel SK, Truger M, Werner RA, Haferlach C, Einsele H, Kretzschmar K, Jelínek T, Rosenwald A, Kortüm KM, Riedel A, Rasche L. Blood. 2024 Nov 14;144(20):2121-2135. doi: 10.1182/blood.2024024590.

Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma. Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JD. Cancer Immunol Res. 2022 Apr 1;10(4):482-497. doi: 10.1158/2326-6066.CIR-21-0778.

 

Last update Publications 04.01.2025

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