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Doctoral Researcher


Name Kira-Isabel Mangold
Affiliation Department of Internal Medicine II
Lehrstuhl für Zelluläre Immuntherapie
Street Versbacher Str. 5
Zip Code 97078
City Würzburg
Email E-mail
Telephone
Homepage
Section Biomedicine
Title of Thesis Project Modulation of cancer immunotherapy by microbial metabolites
Primary Supervisor Junior-Prof. Dr. Maik Luu
Member of Thesis Committee Prof. Dr. Nicolas Schlegel
Prof. Dr. Alexander Visekruna, University Marburg
Conference Contribution
Publication

Dissecting the metabolic signaling pathways by which microbial molecules drive the differentiation of regulatory B cells. Luu M, Krause FF, Monning H, Wempe A, Leister H, Mainieri L, Staudt S, Ziegler-Martin K, Mangold K, Kappelhoff N, Shaul YD, Göttig S, Plaza-Sirvent C, Schulte LN, Bekeredjian-Ding I, Schmitz I, Steinhoff U, Visekruna A. Mucosal Immunol. 2024 Sep 16:S1933-0219(24)00096-5. doi: 10.1016/j.mucimm.2024.09.003. Online ahead of print. 

Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells. Staudt S, Nikolka F, Perl M, Franz J, Leblay N, Yuan XK, Larrayoz M, Lozano T, Warmuth L, Fante MA, Skorpskaite A, Fei T, Bromberg M, San Martin-Uriz P, Rodriguez-Madoz JR, Ziegler-Martin K, Adil-Gholam N, Benz P, Tran Huu P, Stein-Thoeringer C, Schmitt M, Kleigrewe K, Freitag F, Riester Z, Weber J, Mangold K, Ho P, Einsele H, Prosper F, Ellmeier W, Busch D, Visekruna A, Slingerland J, Shouval R, Hiller K, Lasarte JJ, Martinez-Climent JA, Pausch P, Neri P, van den Brink M, Poeck H, Hudecek M, Luu M. bioRxiv [Preprint]. 2025 Feb 4:2024.08.19.608538. doi: 10.1101/2024.08.19.608538. 

Clostridium sporogenes-derived metabolites protect mice against colonic inflammation. Krause FF, Mangold KI, Ruppert AL, Leister H, Hellhund-Zingel A, Lopez Krol A, Pesek J, Watzer B, Winterberg S, Raifer H, Binder K, Kinscherf R, Walker A, Nockher WA, Taudte RV, Bertrams W, Schmeck B, Kühl AA, Siegmund B, Romero R, Luu M, Göttig S, Bekeredjian-Ding I, Steinhoff U, Schütz B, Visekruna A. Gut Microbes. 2024 Jan-Dec;16(1):2412669. doi: 10.1080/19490976.2024.2412669. Epub 2024 Oct 14. 

Last update Publications 20.02.2025

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