Doctoral Researcher


Name Shibo Sun
Affiliation RVZ - Forschungsfeld 2.2 - Kernzentrum

Lehrstuhl für Translationale Zellbiologie
Street Josef-Schneider-Str. 2 D15
Zip Code 97080
City Würzburg
Email
Telephone
Homepage Homepage
Section Biomedicine
Title of Thesis Project Regulation of ferroptosis resistance in NSCLC by ubiquitin proteasome system
Primary Supervisor Prof. José Pedro Friedmann Angeli, PhD
Member of Thesis Committee Prof. Dr. Svenja Meierjohann
Prof. Dr. Hermann Schindelin
Conference Contribution
Publication

Thioredoxin reductase inhibition and glutathione depletion mediated by glaucocalyxin A promote intracellular disulfide stress in gastric cancer cells. Wang L, Sun S, Liu H, Zhang Q, Meng Y, Sun F, Zhang J, Liu H, Xu W, Ye Z, Zhang J, Sun B, Xu J. FEBS J. 2024 Dec;291(23):5276-5289. doi: 10.1111/febs.17301. Epub 2024 Oct 21. 

Protocol for assaying irreversible inhibitors of thioredoxin reductase 1. Sun S, Liu H, Shi W, Zhou H, Wu H, Xu W, Xu J. STAR Protoc. 2024 Sep 20;5(3):103235. doi: 10.1016/j.xpro.2024.103235. Epub 2024 Aug 7. 

Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif. Shi W, Sun S, Liu H, Meng Y, Ren K, Wang G, Liu M, Wu J, Zhang Y, Huang H, Shi M, Xu W, Ma Q, Sun B, Xu J. Redox Biol. 2024 Apr;70:103050. doi: 10.1016/j.redox.2024.103050. Epub 2024 Jan 18. 
Last update Publications 07.07.2025