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Doctoral Researcher


Name Alexandra Klein
Affiliation
Institute Translational Pediatrics
Street Zinklesweg 10
Zip Code 97078
City Würzburg
Email
Telephone
Homepage Homepage
Section Infection & Immunity
Title of Thesis Project The role of S100-alarmins in the perinatal development of respiratory immunity
Primary Supervisor Prof. Dr. Dorothee Viemann
Member of Thesis Committee Prof. Dr. Katrin Heinze
Maria Carmen Aguilar Jurado PhD
Conference Contribution
Publication

Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket. Schichler D, Konle A, Spath EM, Riegler S, Klein A, Seleznev A, Jung S, Wuppermann T, Wetterich N, Borges A, Meyer-Natus E, Havlicek K, Pérez Cabrera S, Niedermüller K, Sajko S, Dohn M, Malzer X, Riemer E, Tumurbaatar T, Djinovic-Carugo K, Dong G, Janzen CJ, Morriswood B. J Cell Sci. 2023 Oct 15;136(20):jcs261548. doi: 10.1242/jcs.261548. Epub 2023 Oct 26. 

Genetic variants of unknown significance in alpha-galactosidase A: Cellular delineation from Fabry disease. Klein A, Klug K, Breyer M, Grüner J, Medala VK, Nordbeck P, Wanner C, Klopocki E, Üçeyler N. J Inherit Metab Dis. 2024 Jul;47(4):805-817. doi: 10.1002/jimd.12743. Epub 2024 Apr 15. 

In vitro characterization of cells derived from a patient with the GLA variant c.376A>G (p.S126G) highlights a non-pathogenic role in Fabry disease. Breyer M, Grüner J, Klein A, Finke L, Klug K, Sauer M, Üçeyler N. Mol Genet Metab Rep. 2023 Nov 25;38:101029. doi: 10.1016/j.ymgmr.2023.101029. eCollection 2024 Mar. 

Endothelial Cell Dysfunction and Hypoxia as Potential Mediators of Pain in Fabry Disease: A Human-Murine Translational Approach. Klug K, Spitzel M, Hans C, Klein A, Schottmann NM, Erbacher C, Üçeyler N. Int J Mol Sci. 2023 Oct 21;24(20):15422. doi: 10.3390/ijms242015422. 

Last update Publications 30.06.2025

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