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ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Rohlfing AK, Kolb K, Sigle M, Ziegler M, Bild A, Münzer P, Sudmann J, Dicenta V, Harm T, Manke MC, Geue S, Kremser M, Chatterjee M, Liang C, von Eysmondt H, Dandekar T, Heinzmann D, Günter M, von Ungern-Sternberg S, Büttcher M, Castor T, Mencl S, Langhauser F, Sies K, Ashour D, Beker MC, Lämmerhofer M, Autenrieth SE, Schäffer TE, Laufer S, Szklanna P, Maguire P, Heikenwalder M, Müller KAL, Hermann DM, Kilic E, Stumm R, Ramos G, Kleinschnitz C, Borst O, Langer HF, Rath D, Gawaz M. Nat Commun. 2022 Apr 5;13(1):1823. doi: 10.1038/s41467-022-29341-1.
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Myocardial Milieu Favors Local Differentiation of Regulatory T Cells. Delgobo M, Weiß E, Ashour D, Richter L, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Mariotti-Ferrandiz E, Rainer PP, Saliba AE, Ludewig B, Hofmann U, Frantz S, Campos Ramos G. Circ Res. 2023 Mar 3;132(5):565-582. doi: 10.1161/CIRCRESAHA.122.322183. Epub 2023 Feb 6.
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Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction. Hardy SA, Liesinger L, Patrick R, Poettler M, Rech L, Gindlhuber J, Mabotuwana NS, Ashour D, Stangl V, Bigland M, Murtha LA, Starkey MR, Scherr D, Hansbro PM, Hoefler G, Campos Ramos G, Cochain C, Harvey RP, Birner-Gruenberger R, Boyle AJ, Rainer PP. JACC Basic Transl Sci. 2023 Aug 16;8(12):1539-1554. doi: 10.1016/j.jacbts.2023.05.010. eCollection 2023 Dec.
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Proinflammatory cytokines set the stage for cardiac damage. Ashour D, Ramos G. Cardiovasc Res. 2024 Mar 13;120(2):109-110. doi: 10.1093/cvr/cvae020.
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Exploring T Cell Receptor Repertoires in Myocardial Diseases. Ashour D, Le Gouge K, Rainer PP, Mariotti-Ferrandiz E, Campos Ramos G. Circ Res. 2024 Jun 7;134(12):1808-1823. doi: 10.1161/CIRCRESAHA.124.323661. Epub 2024 Jun 6.
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An interferon gamma response signature links myocardial aging and immunosenescence. Ashour D, Rebs S, Arampatzi P, Saliba AE, Dudek J, Schulz R, Hofmann U, Frantz S, Cochain C, Streckfuß-Bömeke K, Ramos GC. Cardiovasc Res. 2023 May 4:cvad068. doi: 10.1093/cvr/cvad068. Online ahead of print.
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Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction. Hapke N, Heinrichs M, Ashour D, Vogel E, Hofmann U, Frantz S, Campos Ramos G. J Mol Cell Cardiol. 2022 Dec;173:25-29. doi: 10.1016/j.yjmcc.2022.09.001. Epub 2022 Sep 16.
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The healing myocardium mobilizes a distinct B-cell subset through a CXCL13-CXCR5-dependent mechanism. Heinrichs M, Ashour D, Siegel J, Büchner L, Wedekind G, Heinze KG, Arampatzi P, Saliba AE, Cochain C, Hofmann U, Frantz S, Campos Ramos G. Cardiovasc Res. 2021 Nov 22;117(13):2664-2676. doi: 10.1093/cvr/cvab181.
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Coping with sterile inflammation: between risk and necessity. Ashour D, Delgobo M, Frantz S, Ramos GC. Cardiovasc Res. 2021 May 25;117(6):e84-e87. doi: 10.1093/cvr/cvab157.
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Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging. Delgobo M, Heinrichs M, Hapke N, Ashour D, Appel M, Srivastava M, Heckel T, Spyridopoulos I, Hofmann U, Frantz S, Ramos GC. Front Immunol. 2021 Feb 19;12:584538. doi: 10.3389/fimmu.2021.584538. eCollection 2021.
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Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion. Silva-Vilches C, Pletinckx K, Lohnert M, Pavlovic V, Ashour D, John V, Vendelova E, Kneitz S, Zhou J, Chen R, Reinheckel T, Mueller TD, Bodem J, Lutz MB. PLoS One. 2017 Jul 31;12(7):e0178114. doi: 10.1371/journal.pone.0178114. eCollection 2017.
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