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COVID-19 patients share common, corticosteroid-independent features of impaired host immunity to pathogenic molds. Tappe B, Lauruschkat CD, Strobel L, Pantaleón García J, Kurzai O, Rebhan S, Kraus S, Pfeuffer-Jovic E, Bussemer L, Possler L, Held M, Hünniger K, Kniemeyer O, Schäuble S, Brakhage AA, Panagiotou G, White PL, Einsele H, Löffler J, Wurster S. Front Immunol. 2022 Aug 16;13:954985. doi: 10.3389/fimmu.2022.954985. eCollection 2022.
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Chronic Occupational Mold Exposure Drives Expansion of Aspergillus-Reactive Type 1 and Type 2 T-Helper Cell Responses. Lauruschkat CD, Etter S, Schnack E, Ebel F, Schäuble S, Page L, Rümens D, Dragan M, Schlegel N, Panagiotou G, Kniemeyer O, Brakhage AA, Einsele H, Wurster S, Loeffler J. J Fungi (Basel). 2021 Aug 27;7(9):698. doi: 10.3390/jof7090698.
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Development of a Simple and Robust Whole Blood Assay with Dual Co-Stimulation to Quantify the Release of T-Cellular Signature Cytokines in Response to Aspergillus fumigatus Antigens. Lauruschkat CD, Page L, White PL, Etter S, Davies HE, Duckers J, Ebel F, Schnack E, Backx M, Dragan M, Schlegel N, Kniemeyer O, Brakhage AA, Einsele H, Loeffler J, Wurster S.
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T-Cell Immune Surveillance in Allogenic Stem Cell Transplant Recipients: Are Whole Blood-Based Assays Ready to Challenge ELISPOT?Lauruschkat CD, Page L, Etter S, Weis P, Gamon F, Kraus S, Einsele H, Wurster S, Loeffler J. Open Forum Infect Dis. 2020 Nov 8;8(1):ofaa547. doi: 10.1093/ofid/ofaa547. eCollection 2021 Jan.
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Impact of immunosuppressive and antifungal drugs on PBMC- and whole blood-based flow cytometric CD154+Aspergillus fumigatus specific T-cell quantification. Page L, Lauruschkat CD, Helm J, Weis P, Lazariotou M, Einsele H, Ullmann AJ, Loeffler J, Wurster S. Med Microbiol Immunol. 2020 Mar 31. doi: 10.1007/s00430-020-00665-3. [Epub ahead of print]
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Arginine metabolic control of airway inflammation. Asosingh K, Lauruschkat CD, Alemagno M, Frimel M, Wanner N, Weiss K, Kessler S, Meyers DA, Bennett C, Xu W, Erzurum S. JCI Insight. 2020 Jan 30;5(2). pii: 127801. doi: 10.1172/jci.insight.127801.
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Development and evaluation of a whole blood-based approach for flow cytometric quantification of CD154+ mould-reactive T cells. Weis P, Helm J, Page L, Lauruschkat CD, Lazariotou M, Einsele H, Loeffler J, Ullmann AJ, Wurster S. Med Mycol. 2020 Feb 1;58(2):187-196. doi: 10.1093/mmy/myz038.
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Immunomodulation as a Therapy for Aspergillus Infection: Current Status and Future Perspectives. Lauruschkat CD, Einsele H, Loeffler J. J Fungi (Basel). 2018 Dec 14;4(4). pii: E137. doi: 10.3390/jof4040137. Review.
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Susceptibility of A. fumigatus-specific T-cell assays to pre-analytic blood storage and PBMC cryopreservation greatly depends on readout platform and analytes. Lauruschkat CD, Wurster S, Page L, Lazariotou M, Dragan M, Weis P, Ullmann AJ, Einsele H, Löffler J. Mycoses. 2018 Aug;61(8):549-560. doi: 10.1111/myc.12780. Epub 2018 Jun 11.
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