Institut für Klinische Neurobiologie

The role of RNA binding proteins in motoneuron diseases

Effects of neurotrophic factors CNTF and IGF-1 in mouse models for spinal muscular atrophy and diabetic neuropathy

Initial characterization of mouse Syap1 in the nervous system: search for interaction partners, effects of gene knockdown and knockout, and tissue distribution with focus on the adult brain

Identification of molecular and cellular mechanisms in the pathology of Startle disease due to mutated glycine receptors in human and mouse

Investigation of homeostatic calcium fluxes in hippocampal neurons by means of targeted-esterase induced dye loading (TED)

Whole transcriptome profiling of compartmentalized motoneurons

Study of local protein synthesis in growth cones of embryonic mouse motor neurons

Differential roles of α-, β- and γ-actin isoforms in regulation of cytoskeletal dynamics and stability during axon elongation and collateral branch formation in motoneurons

Investigations into the relevance of glycine receptor intracellular subdomains to receptor channel function

Spinal muscular atrophy with respiratory distress type 1 (SMARD1): Insights from the Nmd2J mouse model and PEGylated IGF-I as an effective therapeutic treatment modality