List Publication MScLS

The program only started in the winter semester 2012/2013. Currently (Jan 2025), of the 81 students who started over the years, 40 continued with a doctoral project in Würzburg. 23 of them have already obtained their doctorate. Additionally, 11 graduates of the program went for a doctorate elsewhere, and of those 7 have already finished their doctoral degree.

39 FOKUS students working or having worked in labs in Würzburg are authors on one or more international peer reviewed papers. FOKUS students in the list below are highlighted in bold print.

Displaying 101 - 186 of 186
Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging. Delgobo M, Heinrichs M, Hapke N, Ashour D, Appel M, Srivastava M, Heckel T, Spyridopoulos I, Hofmann U, Frantz S, Ramos GC. Front Immunol. 2021 Feb 19;12:584538. doi: 10.3389/fimmu.2021.584538. eCollection 2021.
Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. Jansch C, Ziegler GC, Forero A, Gredy S, Wäldchen S, Vitale MR, Svirin E, Zöller JEM, Waider J, Günther K, Edenhofer F, Sauer M, Wischmeyer E, Lesch KP. J Neural Transm (Vienna). 2021 Feb;128(2):225-241. doi: 10.1007/s00702-021-02303-5. Epub 2021 Feb 9.
Activity of Tracheal Cytotoxin of Bordetella pertussis in a Human Tracheobronchial 3D Tissue Model. Kessie DK, Lodes N, Oberwinkler H, Goldman WE, Walles T, Steinke M, Gross R. Front Cell Infect Microbiol. 2021 Jan 19;10:614994. doi: 10.3389/fcimb.2020.614994. eCollection 2020.
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Endres T, Solvie D, Heidelberger JB, Andrioletti V, Baluapuri A, Ade CP, Muhar M, Eilers U, Vos SM, Cramer P, Zuber J, Beli P, Popov N, Wolf E, Gallant P, Eilers M. Mol Cell. 2021 Feb 18;81(4):830-844.e13. doi: 10.1016/j.molcel.2020.12.035. Epub 2021 Jan 15.
Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Signaling Controls Excitability and Long-Term Depression in Oval Nucleus of the BNST. Fiedler D, Sasi M, Blum R, Klinke CM, Andreatta M, Pape HC, Lange MD. J Neurosci. 2021 Jan 20;41(3):435-445. doi: 10.1523/JNEUROSCI.1104-20.2020. Epub 2020 Nov 24.
On the objectivity, reliability, and validity of deep learning enabled bioimage analyses. Segebarth D, Griebel M, Stein N, R von Collenberg C, Martin C, Fiedler D, Comeras LB, Sah A, Schoeffler V, Lüffe T, Dürr A, Gupta R, Sasi M, Lillesaar C, Lange MD, Tasan RO, Singewald N, Pape HC, Flath CM, Blum R. Elife. 2020 Oct 19;9:e59780. doi: 10.7554/eLife.59780.
A global data-driven census of Salmonella small proteins and their potential functions in bacterial virulence. Venturini E, Svensson SL, Maaß S, Gelhausen R, Eggenhofer F, Li L, Cain AK, Parkhill J, Becher D, Backofen R, Barquist L, Sharma CM, Westermann AJ, Vogel J. Microlife. 2020 Oct 17;1(1):uqaa002. doi: 10.1093/femsml/uqaa002. eCollection 2020.
Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease. Wang Z, Becker K, Donadio V, Siedlak S, Yuan J, Rezaee M, Incensi A, Kuzkina A, Orrú CD, Tatsuoka C, Liguori R, Gunzler SA, Caughey B, Jimenez-Capdeville ME, Zhu X, Doppler K, Cui L, Chen SG, Ma J, Zou WQ. JAMA Neurol. 2020 Sep 28;78(1):1-11. doi: 10.1001/jamaneurol.2020.3311. Online ahead of print.
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S, Wolf E. Nat Chem Biol. 2020 Nov;16(11):1179-1188. doi: 10.1038/s41589-020-00652-y. Epub 2020 Sep 28.
The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression. Jessen C, Kreß JKC, Baluapuri A, Hufnagel A, Schmitz W, Kneitz S, Roth S, Marquardt A, Appenzeller S, Ade CP, Glutsch V, Wobser M, Friedmann-Angeli JP, Mosteo L, Goding CR, Schilling B, Geissinger E, Wolf E, Meierjohann S. Oncogene. 2020 Oct;39(44):6841-6855. doi: 10.1038/s41388-020-01477-8. Epub 2020 Sep 25. Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression. Jessen C, Kreß JKC, Baluapuri A, Hufnagel A, Schmitz W, Kneitz S, Roth S, Marquardt A, Appenzeller S, Ade CP, Glutsch V, Wobser M, Friedmann-Angeli JP, Mosteo L, Goding CR, Schilling B, Geissinger E, Wolf E, Meierjohann S. Oncogene. 2020 Oct;39(44):6841-6855. doi: 10.1038/s41388-020-01477-8. Epub 2020 Sep 25.
YBEY is an essential biogenesis factor for mitochondrial ribosomes. Summer S, Smirnova A, Gabriele A, Toth U, Fasemore AM, Förstner KU, Kuhn L, Chicher J, Hammann P, Mitulović G, Entelis N, Tarassov I, Rossmanith W, Smirnov A. Nucleic Acids Res. 2020 Sep 25;48(17):9762-9786. doi: 10.1093/nar/gkaa148.
An RNA-centric view on gut Bacteroidetes. Ryan D, Prezza G, Westermann AJ. Biol Chem. 2020 Sep 24;402(1):55-72. doi: 10.1515/hsz-2020-0230. Print 2020 Nov 18.
Generation of Viable Candida albicans Mutants Lacking the "Essential" Protein Kinase Snf1 by Inducible Gene Deletion. Mottola A, Schwanfelder S, Morschhäuser J. mSphere. 2020 Aug 19;5(4):e00805-20. doi: 10.1128/mSphere.00805-20.
Grad-seq shines light on unrecognized RNA and protein complexes in the model bacterium Escherichia coli. Hör J, Di Giorgio S, Gerovac M, Venturini E, Förstner KU, Vogel J. Nucleic Acids Res. 2020 Aug 19:gkaa676. doi: 10.1093/nar/gkaa676. Online ahead of print.
Induction of BDNF expression in layer II/III and layer V neurons of the motor cortex is essential for motor learning. Andreska T, Rauskolb S, Scheffler N, Lüningschrör P, Sasi M, Signoret-Genest J, Behringer M, Blum R, Sauer M, Tovote P, Sendtner M. J Neurosci. 2020 Jul 10:JN-RM-0288-20. doi: 10.1523/JNEUROSCI.0288-20.2020. Online ahead of print.
Molecular karyotyping and gene expression analysis in childhood cancer patients. Danuta G, Tobias M, Marcus D, Miriam E, Nergiz K, Olesja S, Steffen R, Tanja Z, Christian M, Thomas H, Peter SK, Heather C, Johanna M, Alicia P, Heidi R, Claudia S, Thomas H, Dirk P, Manuela M, Heinz S. J Mol Med (Berl). 2020 Aug;98(8):1107-1123. doi: 10.1007/s00109-020-01937-4. Epub 2020 Jun 23. Correction to: Molecular karyotyping and gene expression analysis in childhood cancer patients. Galetzka D, Müller T, Dittrich M, Endres M, Kartal N, Sinizyn O, Rapp S, Zeller T, Müller C, Hankeln T, Scholz-Kreisel P, Chorzempa H, Mirsch J, Poplawski A, Rossmann H, Spix C, Haaf T, Prawitt D, Marron M, Schmidberger H. J Mol Med (Berl). 2020 Nov;98(11):1657. doi: 10.1007/s00109-020-01986-9.
IL-12 from endogenous cDC1, and not vaccine DC, is required for Th1 induction. Ashour D, Arampatzi P, Pavlovic V, Förstner KU, Kaisho T, Beilhack A, Erhard F, Lutz MB. JCI Insight. 2020 May 21;5(10):135143. doi: 10.1172/jci.insight.135143.
Improved bacterial RNA-seq by Cas9-based depletion of ribosomal RNA reads. Prezza G, Heckel T, Dietrich S, Homberger C, Westermann AJ, Vogel J. RNA. 2020 Apr 28. pii: rna.075945.120. doi: 10.1261/rna.075945.120. [Epub ahead of print]
Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus. Rose C, Casas-Sánchez A, Dyer NA, Solórzano C, Beckett AJ, Middlehurst B, Marcello M, Haines LR, Lisack J, Engstler M, Lehane MJ, Prior IA, Acosta-Serrano Á. Nat Microbiol. 2020 Jul;5(7):909-916. doi: 10.1038/s41564-020-0707-z. Epub 2020 Apr 20..
Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing. Karunakaran MM, Willcox CR, Salim M, Paletta D, Fichtner AS, Noll A, Starick L, Nöhren A, Begley CR, Berwick KA, Chaleil RAG, Pitard V, Déchanet-Merville J, Bates PA, Kimmel B, Knowles TJ, Kunzmann V, Walter L, Jeeves M, Mohammed F, Willcox BE, Herrmann T. Immunity. 2020 Mar 17;52(3):487-498.e6. doi: 10.1016/j.immuni.2020.02.014. Epub 2020 Mar 9.
The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation. El-Merahbi R, Viera JT, Valdes AL, Kolczynska K, Reuter S, Löffler MC, Erk M, Ade CP, Karwen T, Mayer AE, Eilers M, Sumara G. Genes Dev. 2020 Apr 1;34(7-8):495-510. doi: 10.1101/gad.333617.119. Epub 2020 Mar 5.
Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset. Fichtner AS, Karunakaran MM, Gu S, Boughter CT, Borowska MT, Starick L, Nöhren A, Göbel TW, Adams EJ, Herrmann T. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6697-6707. doi: 10.1073/pnas.1909474117. Epub 2020 Mar 5.
Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Forero A, Ku HP, Malpartida AB, Wäldchen S, Alhama-Riba J, Kulka C, Aboagye B, Norton WHJ, Young AMJ, Ding YQ, Blum R, Sauer M, Rivero O, Lesch KP. Neuropharmacology. 2020 May 15;168:108018. doi: 10.1016/j.neuropharm.2020.108018. Epub 2020 Feb 28.
Target gene-independent functions of MYC oncoproteins. Baluapuri A, Wolf E, Eilers M. Nat Rev Mol Cell Biol. 2020 May;21(5):255-267. doi: 10.1038/s41580-020-0215-2. Epub 2020 Feb 18.
Exon-4 Mutations in KRAS Affect MEK/ERK and PI3K/AKT Signaling in Human Multiple Myeloma Cell Lines. Weißbach S, Heredia-Guerrero SC, Barnsteiner S, Großhans L, Bodem J, Starz H, Langer C, Appenzeller S, Knop S, Steinbrunn T, Rost S, Einsele H, Bargou RC, Rosenwald A, Stühmer T, Leich E. Cancers (Basel). 2020 Feb 16;12(2). pii: E455. doi: 10.3390/cancers12020455.
Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription. Cossa G, Roeschert I, Prinz F, Baluapuri A, Silveira Vidal R, Schülein-Völk C, Chang YC, Ade CP, Mastrobuoni G, Girard C, Wortmann L, Walz S, Lührmann R, Kempa S, Kuster B, Wolf E, Mumberg D, Eilers M. Mol Cell. 2020 Mar 19;77(6):1322-1339.e11. doi: 10.1016/j.molcel.2020.01.008. Epub 2020 Jan 31.
Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation. Schäbler S, Amatobi KM, Horn M, Rieger D, Helfrich-Förster C, Mueller MJ, Wegener C, Fekete A. Cell Mol Life Sci. 2020 Dec;77(23):4939-4956. doi: 10.1007/s00018-019-03441-6. Epub 2020 Jan 20.
K5 Capsule and Lipopolysaccharide Are Important in Resistance to T4 Phage Attack in Probiotic E. coli Strain Nissle 1917. Soundararajan M, von Bünau R, Oelschlaeger TA. Front Microbiol. 2019 Nov 29;10:2783. doi: 10.3389/fmicb.2019.02783. eCollection 2019.
A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer. Schmidt S, Gay D, Uthe FW, Denk S, Paauwe M, Matthes N, Diefenbacher ME, Bryson S, Warrander FC, Erhard F, Ade CP, Baluapuri A, Walz S, Jackstadt R, Ford C, Vlachogiannis G, Valeri N, Otto C, Schülein-Völk C, Maurus K, Schmitz W, Knight JRP, Wolf E, Strathdee D, Schulze A, Germer CT, Rosenwald A, Sansom OJ, Eilers M, Wiegering A. Nat Cell Biol. 2019 Nov;21(11):1413-1424. doi: 10.1038/s41556-019-0408-0. Epub 2019 Nov 4.
Comprehensive Flux Modeling of Chlamydia trachomatis Proteome and qRT-PCR Data Indicate Biphasic Metabolic Differences Between Elementary Bodies and Reticulate Bodies During Infection. Yang M, Rajeeve K, Rudel T, Dandekar T. Front Microbiol. 2019 Oct 15;10:2350. doi: 10.3389/fmicb.2019.02350. eCollection 2019.
The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling. Mayer AE, Löffler MC, Loza Valdés AE, Schmitz W, El-Merahbi R, Viera JT, Erk M, Zhang T, Braun U, Heikenwalder M, Leitges M, Schulze A, Sumara G. Sci Signal. 2019 Aug 6;12(593). pii: eaav9150. doi: 10.1126/scisignal.aav9150.
Abnormal α-synuclein deposits in skin nerves: intra- and inter-laboratory reproducibility. Donadio V, Doppler K, Incensi A, Kuzkina A, Janzen A, Mayer G, Volkmann J, Rizzo G, Antelmi E, Plazzi G, Sommer C, Liguori R, Oertel WH. Eur J Neurol. 2019 Oct;26(10):1245-1251. doi: 10.1111/ene.13939. Epub 2019 Aug 2.
An Intragenic Recombination Event Generates a Snf4-Independent Form of the Essential Protein Kinase Snf1 in Candida albicans. Mottola A, Morschhäuser J. mSphere. 2019 Jun 19;4(3). pii: e00352-19. doi: 10.1128/mSphere.00352-19.
The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes. Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S. Cell Rep. 2019 Jun 18;27(12):3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071.
The Impact of Melt Electrowritten Scaffold Design on Porosity Determined by X-Ray Microtomography. Youssef A, Hrynevich A, Fladeland L, Balles A, Groll J, Dalton PD, Zabler S. Tissue Eng Part C Methods. 2019 Jun;25(6):367-379. doi: 10.1089/ten.TEC.2018.0373.
Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells. Wörsdörfer P, Dalda N, Kern A, Krüger S, Wagner N, Kwok CK, Henke E, Ergün S. Sci Rep. 2019 Oct 30;9(1):15663. doi: 10.1038/s41598-019-52204-7.
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang SY, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E. Mol Cell. 2019 May 16;74(4):674-687.e11. doi: 10.1016/j.molcel.2019.02.031. Epub 2019 Mar 27.
Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase. Herold S, Kalb J, Büchel G, Ade CP, Baluapuri A, Xu J, Koster J, Solvie D, Carstensen A, Klotz C, Rodewald S, Schülein-Völk C, Dobbelstein M, Wolf E, Molenaar J, Versteeg R, Walz S, Eilers M. Nature. 2019 Mar;567(7749):545-549. doi: 10.1038/s41586-019-1030-9. Epub 2019 Mar 20.
The aggregation state of α-synuclein deposits in dermal nerve fibers of patients with Parkinson's disease resembles that in the brain. Kuzkina A, Schulmeyer L, Monoranu CM, Volkmann J, Sommer C, Doppler K. Parkinsonism Relat Disord. 2019 Jul;64:66-72. doi: 10.1016/j.parkreldis.2019.03.003. Epub 2019 Mar 9.
A new multilayered membrane for tissue engineering of oral hard- and soft tissue by means of melt electrospinning writing and film casting - An in vitro study. Fuchs A, Youssef A, Seher A, Hartmann S, Brands RC, Müller-Richter UDA, Kübler AC, Linz C. J Craniomaxillofac Surg. 2019 Apr;47(4):695-703. doi: 10.1016/j.jcms.2019.01.043. Epub 2019 Feb 4.
Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy. Klein T, Klug K, Henkel L, Kwok CK, Edenhofer F, Klopocki E, Kurth I, Üçeyler N. Stem Cell Res. 2019 Mar;35:101396. doi: 10.1016/j.scr.2019.101396. Epub 2019 Feb 2.
Medical-grade polycaprolactone scaffolds made by melt electrospinning writing for oral bone regeneration - a pilot study in vitro. Fuchs A, Youssef A, Seher A, Hochleitner G, Dalton PD, Hartmann S, Brands RC, Müller-Richter UDA, Linz C. BMC Oral Health. 2019 Feb 1;19(1):28. doi: 10.1186/s12903-019-0717-5.
Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice. Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, Sendtner M, Ludolph AC, Danzer KM, Lobsiger CS, Freischmidt A, Weishaupt JH. J Exp Med. 2019 Feb 4;216(2):267-278. doi: 10.1084/jem.20180729. Epub 2019 Jan 11.
The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium. Westermann AJ, Venturini E, Sellin ME, Förstner KU, Hardt WD, Vogel J. MBio. 2019 Jan 2;10(1). pii: e02504-18. doi: 10.1128/mBio.02504-18.
Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration. Shashi V, Magiera MM, Klein D, Zaki M, Schoch K, Rudnik-Schöneborn S, Norman A, Lopes Abath Neto O, Dusl M, Yuan X, Bartesaghi L, De Marco P, Alfares AA, Marom R, Arold ST, Guzmán-Vega FJ, Pena LD, Smith EC, Steinlin M, Babiker MO, Mohassel P, Foley AR, Donkervoort S, Kaur R, Ghosh PS, Stanley V, Musaev D, Nava C, Mignot C, Keren B, Scala M, Tassano E, Picco P, Doneda P, Fiorillo C, Issa MY, Alassiri A, Alahmad A, Gerard A, Liu P, Yang Y, Ertl-Wagner B, Kranz PG, Wentzensen IM, Stucka R, Stong N, Allen AS, Goldstein DB; Undiagnosed Diseases Network, Schoser B, Rösler KM, Alfadhel M, Capra V, Chrast R, Strom TM, Kamsteeg EJ, Bönnemann CG, Gleeson JG, Martini R, Janke C, Senderek J. EMBO J. 2018 Dec 3;37(23). pii: e100540. doi: 10.15252/embj.2018100540. Epub 2018 Nov 12.
Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity. Löffler MC, Mayer AE, Trujillo Viera J, Loza Valdes A, El-Merahbi R, Ade CP, Karwen T, Schmitz W, Slotta A, Erk M, Janaki-Raman S, Matesanz N, Torres JL, Marcos M, Sabio G, Eilers M, Schulze A, Sumara G. EMBO J. 2018 Nov 15;37(22):e99182. doi: 10.15252/embj.201899182. Epub 2018 Nov 2.
Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerve growth factor gene potentially associated with hereditary sensory and autonomic neuropathy type 5. Klein T, Henkel L, Klug K, Kwok CK, Klopocki E, Üçeyler N. Stem Cell Res. 2018 Dec;33:171-174. doi: 10.1016/j.scr.2018.10.017. Epub 2018 Oct 12.
Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells. Mekala SR, Wörsdörfer P, Bauer J, Stoll O, Wagner N, Reeh L, Loew K, Eckner G, Kwok CK, Wischmeyer E, Dickinson ME, Schulze H, Stegner D, Benndorf RA, Edenhofer F, Pfeiffer V, Kuerten S, Frantz S, Ergün S. Circ Res. 2018 Aug 31;123(6):686-699. doi: 10.1161/CIRCRESAHA.117.312526.
Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Klein T, Günther K, Kwok CK, Edenhofer F, Üçeyler N. Stem Cell Res. 2018 Aug;31:222-226. doi: 10.1016/j.scr.2018.08.009. Epub 2018 Aug 10.
The Probiotic Escherichia coli Strain Nissle 1917 Combats Lambdoid Bacteriophages stx and λ. Bury S, Soundararajan M, Bharti R, von Bünau R, Förstner KU, Oelschlaeger TA. Front Microbiol. 2018 May 29;9:929. doi: 10.3389/fmicb.2018.00929. eCollection 2018.
Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation. Milanos S, Kuenzel K, Gilbert DF, Janzen D, Sasi M, Buettner A, Frimurer TM, Villmann C. Biol Chem. 2018 May 24;399(6):549-563. doi: 10.1515/hsz-2017-0262.
C. elegans Blastomeres Clear the Corpse of the Second Polar Body by LC3-Associated Phagocytosis. Fazeli G, Stetter M, Lisack JN, Wehman AM. Cell Rep. 2018 May 15;23(7):2070-2082. doi: 10.1016/j.celrep.2018.04.043.
Dimension-Based Design of Melt Electrowritten Scaffolds. Hrynevich A, Elçi BŞ, Haigh JN, McMaster R, Youssef A, Blum C, Blunk T, Hochleitner G, Groll J, Dalton PD. Small. 2018 May;14(22):e1800232. doi: 10.1002/smll.201800232. Epub 2018 Apr 30.
Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice. Yuan X, Klein D, Kerscher S, West BL, Weis J, Katona I, Martini R. J Neurosci. 2018 May 9;38(19):4610-4620. doi: 10.1523/JNEUROSCI.3030-17.2018. Epub 2018 Apr 30.
An open source tool for automatic spatiotemporal assessment of calcium transients and local 'signal-close-to-noise' activity in calcium imaging data. Prada J, Sasi M, Martin C, Jablonka S, Dandekar T, Blum R. PLoS Comput Biol. 2018 Mar 30;14(3):e1006054. doi: 10.1371/journal.pcbi.1006054. eCollection 2018 Mar.
Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells. Vendelova E, Ashour D, Blank P, Erhard F, Saliba AE, Kalinke U, Lutz MB. Front Immunol. 2018 Feb 28;9:333. doi: 10.3389/fimmu.2018.00333. eCollection 2018. Review.
The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals. Fichtner AS, Karunakaran MM, Starick L, Truman RW, Herrmann T. Front Immunol. 2018 Feb 23;9:265. doi: 10.3389/fimmu.2018.00265. eCollection 2018.
Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C, Pluchino S. Cell Stem Cell. 2018 Mar 1;22(3):355-368.e13. doi: 10.1016/j.stem.2018.01.020. Epub 2018 Feb 22.
Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3. Jansch C, Günther K, Waider J, Ziegler GC, Forero A, Kollert S, Svirin E, Pühringer D, Kwok CK, Ullmann R, Maierhofer A, Flunkert J, Haaf T, Edenhofer F, Lesch KP. Stem Cell Res. 2018 Apr;28:136-140. doi: 10.1016/j.scr.2018.02.005. Epub 2018 Feb 13.
Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle. Büchel G, Carstensen A, Mak KY, Roeschert I, Leen E, Sumara O, Hofstetter J, Herold S, Kalb J, Baluapuri A, Poon E, Kwok C, Chesler L, Maric HM, Rickman DS, Wolf E, Bayliss R, Walz S, Eilers M. Cell Rep. 2017 Dec 19;21(12):3483-3497. doi: 10.1016/j.celrep.2017.11.090.
PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters. Gerlach JM, Furrer M, Gallant M, Birkel D, Baluapuri A, Wolf E, Gallant P. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9224-E9232. doi: 10.1073/pnas.1705816114. Epub 2017 Oct 16.
Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single-use bioreactors. Kwok CK, Ueda Y, Kadari A, Günther K, Heron A, Schnitzler AC, Rook M, Edenhofer F. J Tissue Eng Regen Med. 2018 Feb;12(2):e1076-e1087. doi: 10.1002/term.2435. Epub 2017 Oct 2.
Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Forero A, Rivero O, Wäldchen S, Ku HP, Kiser DP, Gärtner Y, Pennington LS, Waider J, Gaspar P, Jansch C, Edenhofer F, Resink TJ, Blum R, Sauer M, Lesch KP. Front Cell Neurosci. 2017 Sep 26;11:307. doi: 10.3389/fncel.2017.00307. eCollection 2017.
Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion. Silva-Vilches C, Pletinckx K, Lohnert M, Pavlovic V, Ashour D, John V, Vendelova E, Kneitz S, Zhou J, Chen R, Reinheckel T, Mueller TD, Bodem J, Lutz MB. PLoS One. 2017 Jul 31;12(7):e0178114. doi: 10.1371/journal.pone.0178114. eCollection 2017.
The Snf1-activating kinase Sak1 is a key regulator of metabolic adaptation and in vivo fitness of Candida albicans.  Ramírez-Zavala B, Mottola A, Haubenreißer J, Schneider S, Allert S, Brunke S, Ohlsen K, Hube B, Morschhäuser J. Mol Microbiol. 2017 Jun;104(6):989-1007. doi: 10.1111/mmi.13674. Epub 2017 Apr 18.
Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene. Seefried L, Müller-Deubert S, Krug M, Youssef A, Schütze N, Ignatius A, Jakob F, Ebert R. Exp Cell Res. 2017 May 15;354(2):103-111. doi: 10.1016/j.yexcr.2017.03.031. Epub 2017 Mar 16.
Neurobiology of local and intercellular BDNF signaling. Sasi M, Vignoli B, Canossa M, Blum R. Pflugers Arch. 2017 Jun;469(5-6):593-610. doi: 10.1007/s00424-017-1964-4. Epub 2017 Mar 9. Review. Erratum in: Pflugers Arch. 2017 Jun;469(5-6):611
Additive manufacturing of polymer melts for implantable medical devices and scaffolds. Youssef A, Hollister SJ, Dalton PD. Biofabrication. 2017 Feb 28;9(1):012002. doi: 10.1088/1758-5090/aa5766.
The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth. Weiste C, Pedrotti L, Selvanayagam J, Muralidhara P, Fröschel C, Novák O, Ljung K, Hanson J, Dröge-Laser W. PLoS Genet. 2017 Feb 3;13(2):e1006607. doi: 10.1371/journal.pgen.1006607. eCollection 2017 Feb.
Reported bed net ownership and use in social contacts is associated with uptake of bed nets for malaria prevention in pregnant women in Ghana. Ernst KC, Erly S, Adusei C, Bell ML, Kessie DK, Biritwum-Nyarko A, Ehiri J. Malar J. 2017 Jan 4;16(1):13. doi: 10.1186/s12936-016-1660-4.
Abrogation of Gap Junctional Communication in ES Cells Results in a Disruption of Primitive Endoderm Formation in Embryoid Bodies. Wörsdörfer P, Bosen F, Gebhardt M, Russ N, Zimmermann K, Komla Kessie D, Sekaran T, Egert A, Ergün S, Schorle H, Pfeifer A, Edenhofer F, Willecke K. Stem Cells. 2017 Apr;35(4):859-871. doi: 10.1002/stem.2545. Epub 2016 Dec 20.
High GDF-15 Serum Levels Independently Correlate with Poorer Overall Survival of Patients with Tumor-Free Stage III and Unresectable Stage IV Melanoma. Weide B, Schäfer T, Martens A, Kuzkina A, Uder L, Noor S, Garbe C, Harter PN, Mittelbronn M, Wischhusen J. J Invest Dermatol. 2016 Dec;136(12):2444-2452. doi: 10.1016/j.jid.2016.07.016. Epub 2016 Oct 2.
Different promoter affinities account for specificity in MYC-dependent gene regulation. Lorenzin F, Benary U, Baluapuri A, Walz S, Jung LA, von Eyss B, Kisker C, Wolf J, Eilers M, Wolf E. Elife. 2016 Jul 27;5:e15161. doi: 10.7554/eLife.15161.
Rapid Monolayer Neural Induction of induced Pluripotent Stem Cells Yields Stably Proliferating Neural Stem Cell. Günther K, Appelt-Menzel A, Kwok CK, Walles H, Metzger M, Edenhofer F. J Stem Cell Res Ther. 2016 Jun 20; 6:341. doi:10.4172/2157-7633.1000341.
Phospholipases D1 and D2 Suppress Appetite and Protect against Overweight. Trujillo Viera J, El-Merahbi R, Nieswandt B, Stegner D, Sumara G. PLoS One. 2016 Jun 14;11(6):e0157607. doi: 10.1371/journal.pone.0157607. eCollection 2016.
Fibre pulsing during melt electrospinning writing. Hochleitner G, Youssef A, Hrynevich A, Haigh JN, Jungst T, Groll J, Dalton PD. BioNanoMaterials. ISSN (Online) 2193-066X, ISSN (Print) 2193-0651, DOI: 10.1515/bnm-2015-0022, May 2016
A Candida albicans regulator of disseminated infection operates primarily as a repressor and governs cell surface remodeling. Böhm L, Muralidhara P, Pérez JC. Mol Microbiol. 2016 Apr;100(2):328-44. doi: 10.1111/mmi.13320. Epub 2016 Feb 19.
Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology. Candemir E, Kollert L, Weißflog L, Geis M, Müller A, Post AM, O'Leary A, Harro J, Reif A, Freudenberg F. Eur Neuropsychopharmacol. 2016 Apr;26(4):741-55. doi: 10.1016/j.euroneuro.2016.01.008. Epub 2016 Jan 28.
Effects of Prednisolone on Disease Progression in Antiretroviral-Untreated HIV Infection: A 2-Year Randomized, Double-Blind Placebo-Controlled Clinical Trial. Kasang C, Kalluvya S, Majinge C, Kongola G, Mlewa M, Massawe I, Kabyemera R, Magambo K, Ulmer A, Klinker H, Gschmack E, Horn A, Koutsilieri E, Preiser W, Hofmann D, Hain J, Müller A, Dölken L, Weissbrich B, Rethwilm A, Stich A, Scheller C. PLoS One. 2016 Jan 26;11(1):e0146678. doi: 10.1371/journal.pone.0146678. eCollection 2016.
Species Specific Differences of CD1d Oligomer Loading In Vitro. Paletta D, Fichtner AS, Starick L, Porcelli SA, Savage PB, Herrmann T. PLoS One. 2015 Nov 24;10(11):e0143449. doi: 10.1371/journal.pone.0143449. eCollection 2015.
Draft Genome Sequence of the Moderately Heat-Tolerant Lactococcus lactis subsp. lactis bv. diacetylactis Strain GL2 from Algerian Dromedary Milk. Gabed N, Yang M, Bey Baba Hamed M, Drici H, Gross R, Dandekar T, Liang C. Genome Announc. 2015 Nov 19;3(6). pii: e01334-15. doi: 10.1128/genomeA.01334-15.
Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice. Masic A, Valencia Hernandez AM, Hazra S, Glaser J, Holzgrabe U, Hazra B, Schurigt U. PLoS One. 2015 Nov 10;10(11):e0142386. doi: 10.1371/journal.pone.0142386. eCollection 2015.
Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice. Masic A, Valencia Hernandez AM, Hazra S, Glaser J, Holzgrabe U, Hazra B, Schurigt U. PLoS One. 2015 Nov 10;10(11):e0142386. doi: 10.1371/journal.pone.0142386. eCollection 2015.
Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus). Fichtner AS, Paletta D, Starick L, Schumann RF, Niewiesk S, Herrmann T. Immunology. 2015 Dec;146(4):618-29. doi: 10.1111/imm.12532. Epub 2015 Oct 14.
Whole transcriptome profiling reveals the RNA content of motor axons. Briese M, Saal L, Appenzeller S, Moradi M, Baluapuri A, Sendtner M. Nucleic Acids Res. 2016 Feb 29;44(4):e33. doi: 10.1093/nar/gkv1027. Epub 2015 Oct 12.
The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d-glycolipid binding of iNKT TCRs. Paletta D, Fichtner AS, Hahn AM, Starick L, Beyersdorf N, Monzon-Casanova E, Mueller TD, Herrmann T. Eur J Immunol. 2015 Jul;45(7):2122-33. doi: 10.1002/eji.201545534. Epub 2015 May 12.

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